Left Ventricular Hypertrophy in CKD Patients

ConditionLeft Ventricular Hypertrophy

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-75

SponsorSohag University

About this trial

The goal of this observational study is to determine the prevalence of left ventricular hypertrophy among patients with chronic kidney disease at Sohag University Hospital and assess the effect of erythropoietin therapy on left ventricular mass and geometry in anemic CKD patients.

The main question it aims to answer is:

Does erythropoietin therapy mitigate or even reverse LVH and improve cardiac geometry ?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults (≥18 years) diagnosed with CKD stages 3-5.

Stable clinical condition for ≥3 months.

Anemia (Hb <10 g/dL) for cohort phase.

Willingness to participate and provide informed consent.

Disqualifiers

Valvular or ischemic heart disease.

Uncontrolled hypertension (BP >180/110 mmHg).

Acute coronary syndrome or decompensated heart failure in the past 3 months.

Malignancy or active infection

Trial population

study population is adults age (18-75)years, diagnosed with CKD stage 3-5 .

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

transthoracic echocardiography
Radiation
Standard transthoracic echocardiography will be performed for all participants, measuring: * Left ventricular end-diastolic diameter (LVEDD) * Interventricular septal thickness (IVSD) * Posterior wall thickness (PWD) * Left ventricular mass (LVM) * Left ventricular mass index (LVMI = LVM/body surface area)

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

Change in LVMI following erythropoietin therapy in anemic CKD patients.

Time frame

- baseline transthoracic echocardiography will be performed for all group study.

Secondary outcomes

Association between hemoglobin level and LVMI.

Time frame

6 months of erythropoitin therapy , transthoracic echocardiography will be performed for all group study.

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sohag University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: