Local Anaesthetic Spread and Sensory Block Range of the Retro-superior Costotransverse Ligament Space Block

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNanjing First Hospital, Nanjing Medical University

About this trial

The aim of this clinical trial is to investigate the effects of local anesthetic diffusion range and sensory block range during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral block) in patients undergoing CT-guided lung nodule localization. The main issue of the study is to determine the differences in the diffusion range and sensory block range of local anesthetics between the retro-SCTLB and TPVB nerve block methods.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

aged 18-80 years

BMI 18-30 kg/m²

ASA classification I-III

Disqualifiers

Allergy to the study drug or local anesthetic;

History of opioid abuse;

Pre-existing skin infection at the puncture site of ITPN or TPVB;

Peripheral infectious neuropathy;

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ultrasound-guided retro-SCTLB

    Procedure/Surgery

    Patients undergoing CT-guided lung nodule localization were selected for the study. Before the surgery, the retro-SCTLB was performed under ultrasound guidance.

  • Ultrasound-guided TPVB

    Procedure/Surgery

    Patients undergoing CT-guided lung nodule localization were selected for the study. Before the surgery, the TPVB was performed under ultrasound guidance.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: retro-SCTLB groupExperimental treatment 1 intervention
Group B: TPVB groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Spread of local anesthetic into the paravertebral space

Observation of incidence and thoracic level of local anesthetic spread into the paravertebral space with CT by a researcher who was blinded to group allocation

Time frame
15 minutes after completion of the nerve block

Secondary outcomes

1

The range of the local anesthetic spreads to the intercostal space

Observation of incidence and thoracic level of local anesthetic spread into the intercostal space with CT by a researcher who was blinded to group allocation

Time frame
15 minutes after completion of the nerve block
2

Observation of local anesthetic spread cephalocaudally in the erector spinae plane

Observation of incidence and thoracic level of local anesthetic spread into the erector spinae plane cephalocaudally with CT by a researcher who was blinded to group allocation.

Time frame
15 minutes after completion of the nerve block
3

The range of the local anesthetic spread to the epidural space

Observation of incidence and thoracic level of local anesthetic spread into the epidural space with CT by a researcher who was blinded to group allocation

Time frame
15 minutes after completion of the nerve block
4

The range of the local anesthetic spread to the anterolateral vertebrae (sympathetic ganglion).

Observation of incidence and thoracic level of local anesthetic spread into the anterolateral vertebrae (sympathetic ganglion) with CT by a researcher who was blinded to group allocation

Time frame
15 minutes after completion of the nerve block

Other outcomes

Sponsors and contacts

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