Local Anesthetic Infiltration for Pain Control After Orthopedic Wide Excision

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorSeoul National University Hospital

About this trial

This study evaluates whether injecting a local anesthetic mixture (ropivacaine, morphine, ketorolac, and epinephrine) under the skin at the incision site before wound closure reduces pain after orthopedic wide excision surgery for bone or soft tissue tumors. Participants will be randomly assigned to receive either the local anesthetic mixture or a saline control injection. Neither participants nor the study team assessing outcomes will know which treatment was given. The main goal is to determine whether this injection reduces the amount of opioid pain medication needed during the first 24 hours after surgery. The study will also assess pain scores, nausea and vomiting, and quality of recovery.

Eligibility criteria

Qualifiers

Scheduled to undergo elective orthopedic wide excision surgery under general anesthesia

American Society of Anesthesiologists (ASA) Physical Status Classification 1, 2, or 3

Age 19 years or older

Disqualifiers

Unwilling to provide informed consent

History of allergy to local anesthetics

History of chronic pain

Use of opioid analgesics within 24 hours before surgery

Trial design

Treatments tested in this trial

  • Ropivacaine-Morphine-Ketorolac-Epinephrine-Cefuroxime Mixture
  • Cefuroxime-Saline Mixture

Treatment groups

58 Participants
are divided into 2 treatment groups

Locations

This trial has no locations