Long-term Effect of Silver Diamine Fluoride on the Dentin-Pulp Complex in Primary Teeth
ConditionSilver Diamine Fluoride
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7-10
SponsorCairo University
About this trial
Children with primary teeth with dentin carious lesions without pulp involvement, who have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or with Resin Modified Glass Ionomer alone, will be retrieved from the Pediatric Dentistry and Dental Public Health Department records. The aim of the study, a detailed description of the procedure, and how the tooth will be used, will be explained to the parents and their child, and written informed consent from the parents and assent from the child will be obtained.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Treated primary teeth with clinical or radiographic signs of infection
Trial population
Children with primary teeth that have previously been treated with either Silver Diamine Fluoride (SDF) followed by Resin Modified Glass Ionomer or Resin Modified Glass Ionomer alone.
Trial design
Design model
Other
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
6 Participants
are grouped into 2 trial groupsGroup A: Arm 1
Group B: Arm 2
Trial outcomes
Primary outcomes
1
Histological evaluation of dental pulp under light microscope
After teeth extraction, they will be fixed in a 10% formalin buffer for at least 48 hours, after which they will be decalcified in 10% nitric acid for 7 days. Then they will be embedded in paraffin, and mesiodistal histological sections approximately 8 μm thick will be cut. Sections will be stained with hematoxylin and Eosin, and a qualitative histological evaluation of dental pulp will be performed under light microscopy.
Time frame
7 days after extractionSponsors and contacts
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Source ClinicalTrials.gov