About this trial
Myopia is a leading cause of visual impairment worldwide, with prevalence rising rapidly among children. Growing evidence suggests that environmental and behavioral factors play a dominant role in ocular growth; however, current studies typically isolate single components of the visual environment, such as near work or light intensity, limiting investigators' understanding of how multiple visual stimuli interact within individuals over time. The retina is continuously exposed to a dynamic "visual diet," encompassing viewing distance, illuminance, spectral composition of light, and temporal viewing patterns, as well as associated visuomotor responses such as eye vergence and pupil dynamics. A critical barrier to myopia prevention is the lack of longitudinal, quantitative measurements that integrate these factors in real-world settings during childhood ocular development.
The long-term goal of this project is to prevent myopia onset and slow myopia progression through individualized, patient-centered monitoring and modification of the visual diet. The overall objective of this proposal is to longitudinally characterize visual diet and visuomotor behavior in children and to identify the most influential environmental and physiological factors driving myopia onset and progression. The investigators will conduct a 3-year longitudinal observational study enrolling 60 children aged 7-12 years, including myopic children and non-myopic children stratified by risk of myopia progression.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age: 7-12 years old (inclusive)
Astigmatism of < 1.50D
Stereopsis equal or better 100 seconds of arc
Normal binocular functions.
Disqualifiers
History of refractive surgery or myopia control
Binocular abnormalities
Ocular and systemic pathologies
Developmental delay
Trial population
Participants will be selected from the Pediatric Clinic at the College and from the local community.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Refractive error (D)
Measured with an autorefractor
Axial length (mm)
Measured with a biometer
Viewing distance (cm)
Measured using the Visual Environment Evaluation Tool (VEET). VEET contains multiple time-of-flight (ToF) infrared sensors embedded in the temple arms of the glasses.The sensors emit infrared light toward objects in front of the wearer. The device measures the time required for the reflected infrared light to return to the sensor. Using the speed of light, the system calculates the distance between the eye/glasses and the viewed object.
Illuminance (lux)
Measured with the Visual Environment Evaluation Tool (VEET). VEET uses photometric light sensors that detect the light intensity. The sensors convert incoming light into electrical signals proportional to brightness, and the device reports illuminance in lux, the standard unit for light exposure.
Secondary outcomes
Height (cm)
Using a stadiometer.
Arm length (cm)
Measured using a tape measure.
Accommodative facility
Using +/- 2.00 D flippers
Sponsors and contacts
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