Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorKocaeli University
About this trial
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.
Researcher aimed to compare the effects of two different PEEP application methods on intraoperative hemodynamics, respiratory mechanics, and gas exchange, as well as postoperative extubation times, respiratory complications (atelectasis, need for non invasive mechanical ventilatıon, need for re-entubatıon) length of stay in the intensive care unit, and discharge times.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients scheduled for elective on-pump coronary artery bypass graft surgery via median sternotomy
Patients between the ages of 18 and 70
ASA (American Society of Anesthesiologists) physical status classification II-III
Disqualifiers
Patients with an ejection fraction below 35%
Patients who did not consent to participate in the study
Patients undergoing emergency surgery
Patients who are allergic to the anesthetic drugs used
Trial population
Patients who will undergo elective on-pump coronary artery bypass graft surgery under general anesthesia
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
86 Participants
are grouped into 2 trial groupsGroup A: Fixed PEEP
Group B: Indıvıdalızed PEEP
Trial outcomes
Primary outcomes
1
Effects on intraoperative oxygenation, hemodynamics, lung compliance and airway pressures
Data will be recorded during surgery and the first 24 hours after extubation.
Time frame
First one daySponsors and contacts
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Source ClinicalTrials.gov