Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorInstitute of Liver and Biliary Sciences, India

About this trial

Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All prospective voluntary healthy liver donor of age 18-55

Disqualifiers

Type C/D Portal vein anatomy

Left sided Gallbladder

Right Posterior Graft

Recipients undergoing Hepaticojejunostomy

Trial design

Design model

Parallel

Treatments tested in this trial

  • Magnetic Resonance Cholangiopancreatography

    Diagnostic test

    Magnetic Resonance Cholangiopancreatography is being excluded from list of Investigation as part of Non inferiority trial

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: No MRCP GROUPNo intervention 0 interventions
Group B: MRCP GROUPExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

To identify factors causing early biliary complications like type and number of arterial & biliary reconstruction, type of graft, number & size of Bile ducts in donor in both groups

Time frame
6 month of postop

Secondary outcomes

1

Donor biliary complications in both group

Bile leak or strictures in Liver Donors

Time frame
1 month of postoperative period
2

Identify Risk factors for early Biliary complications in recipients

Identify Risk factors for early Biliary complications in recipients

Time frame
till 6 months of Post operative period of Liver transplant

Other outcomes

Sponsors and contacts

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