About this trial
The goal of this study is to learn if an online computerized training program improves processing speed, attention, and working memory in children with a primary brain tumor during and after active cancer treatment. The main questions it aims to answer are:
1. Is the cognitive intervention feasible to administer to children with brain tumors during and after cancer treatment?, 2. Is the cognitive intervention acceptable to children and caregivers?, and 3. Does the cognitive intervention improve neuropsychological functioning?
There is no comparison group for this study.
Participants will:
1. Complete an online computerized cognitive training program for approximately 15 minutes per day, 5 days a week, for 8 weeks; 2. Have weekly check-ins with the cognitive coach, 3. Complete a survey at the end of the cognitive training program, and 4. Complete pre- and post- neuropsychological testing.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosis of a primary brain tumor,
Children and young adults 5 to 25 years of age at the time of enrollment,
Within five years of initial brain tumor diagnosis,
Receiving care through the Johns Hopkins neuro-oncology program.
Disqualifiers
Significant visual, hearing, motor, or cognitive impairment that precludes participation in computerized cognitive training program;
Acute medical status (e.g., significant risk for mortality within 3-months of diagnosis).
Trial design
Single group
Treatments tested in this trial
Online computerized cognitive training intervention focused on processing speed.
BehavioralThis online cognitive training program aims to improve processing speed through computerized cognitive exercises. Participants will complete approximately 15 minutes of training, 5 days per week for 8 weeks. Weekly check-ins with a cognitive coach will assist with engagement and problem solve any barriers.
Treatment groups
Trial outcomes
Primary outcomes
Feasibility - Enrollment
Study enrollment rate.
Feasibility - Participant Retention
Number of participants who complete the computerized brain training program.
Feasibility - Intervention Adherence
Number of levels completed in the cognitive training program. Qualitative feedback regarding barriers and facilitators to engagement will also we collected to provide descriptive context.
Feasibility - Total Intervention Time
Total time spent completing the cognitive training program exercises.
Secondary outcomes
Cognitive Training Task-Based Performance
Changes in neuropsychological functioning, as measured by the train-to-task activity.
Processing Speed
Changes in processing speed as measured by the NIH toolbox.
Attention
Changes in attention as measured by the NIH toolbox.
Working Memory
Changes in working memory as measured by the NIH toolbox.
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: