This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients admitted to the Surgical Intensive Care Unit at Zagazig University Hospitals.
Age ≥18 years.
Both sexes.
Patients requiring invasive controlled mechanical ventilation in the ICU and expected to require mechanical ventilation for at least 72 hours.
Enrollment within the first 8 hours after initiation of invasive mechanical ventilation.
Predominant spontaneous breathing or weaning modes during the first 48 hours.
Severe hemodynamic instability precluding standardized measurements.
Prolonged mechanical ventilation prior to ICU admission.
Pregnancy.
Adult patients requiring invasive mechanical ventilation and admitted to the Surgical Intensive Care Unit at Zagazig University Hospitals.
Cohort
Prospective
Not listed
28-Day Mortality
All-cause mortality within 28 days after initiation of invasive mechanical ventilation.
Driving Pressure and Plateau Pressure
Correlation between mechanical power and driving pressure and plateau pressure at 24, 48, and 72 hours.
Ventilator-Free Days
Number of ventilator-free days within the first 28 days.
ICU Length of Stay
Duration of stay in the intensive care unit
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