Menopausal Impact on Skin Aging Among Egyptian Women
ConditionSkin Aging
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age40-60
SponsorSohag University
About this trial
The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60.
The main question the study wants to answer is:
Does menopause cause any changes in how the skin ages?
To find out, the participants will be divided into two groups based on their menstrual history:
* Women who have not yet gone through menopause (premenopausal) * Women who have already gone through menopause (postmenopausal) A researcher will examine the skin of women in both groups to look for signs of aging. Then, the results will be compared to see if there are any differences between the two groups.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Females aged 40 to 60 years
Egyptian nationality or residency
Ability to provide informed consent
Premenopausal (still menstruating regularly)
Disqualifiers
Menopausal transition (Perimenopausal women
Menopause induced by hysterectomy
History of hormone therapy in the past 6 months
Active dermatological conditions affecting the face (e.g. eczema, psoriasis)
Trial population
This study will include Egyptian women between the ages of 40 and 60 years who are either premenopausal or postmenopausal, based on their menstrual history. participants must be in good general health and not currently receiving hormone replacement therapy or any treatment known to affect skin condition.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Dermoscopy
Devicedermoscopic assessment of skin aging signs
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Clinical skin aging severity using Glogau Photoaging Scale
The Glogau Photoaging Scale will be used for evaluation. Facial assessment will be conducted both at rest and during facial animation to observe dynamic changes. Participant will be categorized into 4 types or grades where type 1 is mild skin aging and type 4 is severe skin aging
Time frame
Assessed once at baseline during participant's visit2
Dermoscopic skin aging score using the dermoscopic photoaging assessment scale
this scale is used to assess facial skin aging. The face will be divided into four regions: the forehead, right cheek, left cheek, and chin. Each region will be examined for the presence of the following features: yellowish discoloration, yellow papules, white linear areas indicating skin atrophy, lentigines, hypo- or hyperpigmented macules, telangiectasia, actinic keratoses, senile comedones, deep wrinkles, superficial wrinkles, and criss-cross wrinkles. Scoring follows a binary (yes/no) approach, where the presence of a given feature in any of the four regions scores one point, yielding a total possible score ranging from 0 to 44. a higher score means worse outcome.
Time frame
Assessed once at baseline during participant 's visitSecondary outcomes
1
Prevalence of specific clinical and dermoscopic aging features
Time frame
Recorded during clinical and dermoscopic assessment at baseline2
Correlation between menopausal status and severity of skin aging
Time frame
Assessed once at baseline during participant's visit based on menopausal history and skin aging scores3
Correlation between menopausal duration and skin aging
Time frame
Menopausal duration collected via history at baseline; skin aging assessed at baselineLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: