Health TrialsbyHealthPanel

mFFE MRI Versus CT for Cortical Bone Evaluation in Knee Osteoarthritis

ConditionsOsteoarthritis, KneeBone Diseases
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorAssiut University

About this trial

This cross-sectional study aims to evaluate the accuracy of multi-echo fast field echo (mFFE) MRI in depicting cortical bone changes in knee osteoarthritis compared with CT.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

- Age 40 years or older

Clinically suspected or confirmed knee osteoarthritis

Able and willing to provide informed consent

Disqualifiers

- Implanted electronic devices (pacemakers, ICDs, neurostimulators, cochlear implants)

Metallic foreign bodies in the eyes or orbits

Ferromagnetic cerebral aneurysm clips

Implantable infusion pumps

Trial population

Patients aged 40 years or older with clinically suspected or confirmed knee osteoarthritis attending the Diagnostic and Interventional Radiology Department at Assiut University Hospital.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

80 Participants
are grouped into 1 trial group
Group A: Single cohort: Patients with knee osteoarthritis

Trial outcomes

Primary outcomes

1

Diagnostic accuracy of mFFE MRI for cortical bone changes

Overall diagnostic accuracy percentage of multi-echo fast field echo MRI in detecting cortical bone degenerative changes in knee osteoarthritis, using CT as the reference standard

Time frame
Baseline

Secondary outcomes

1

Sensitivity of mFFE MRI for cortical bone changes

Sensitivity percentage of multi-echo fast field echo MRI in detecting cortical bone degenerative changes in knee osteoarthritis, using CT as the reference standard

Time frame
Baseline
2

Specificity of mFFE MRI for cortical bone changes

Specificity percentage of multi-echo fast field echo MRI in detecting cortical bone degenerative changes in knee osteoarthritis, using CT as the reference standard

Time frame
Baseline
3

Detection of subchondral sclerosis

Number of cases in which mFFE MRI correctly identifies subchondral sclerosis compared with CT

Time frame
Baseline
4

Detection of osteophytes

Number of cases in which mFFE MRI correctly identifies osteophytes compared with CT

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: