Midpoint Transverse Process to Pleura (MTP) Block vs Erector Spinae Plane (ESP) Block for Acute Herpes Zoster (HZ) Pain

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorTanta University

About this trial

The aim of this study is to compare the analgesic efficacy and safety of ultrasound-guided midpoint transverse process block versus ultrasound-guided erector spinae plane block in patients suffering from thoracic herpes zoster pain.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 21-60 years.

Both sexes.

American Society of Anesthesiologists (ASA) physical status I-II.

Acute thoracic herpes zoster within 30 days of rash onset.

Disqualifiers

Refusal to participate.

Coagulopathy or anticoagulant therapy.

Infection at puncture site.

Allergy to study drugs.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Midpoint transverse process to pleura block

    Other intervention

    Patients will receive ultrasound-guided midpoint transverse process to pleura block using 10 mL 0.25% bupivacaine + 40 mg methylprednisolone.

  • Erector spinae plane block

    Other intervention

    Patients will receive ultrasound -guided erector spinae plane block using 10 mL 0.25% bupivacaine + 40 mg methylprednisolone.

Treatment groups

90 Participants
are divided into 2 treatment groups
Group A: Group MTPOther 1 intervention
Group B: Group ESPOther 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of post-herpatic neuralgia

Incidence of post-herpatic neuralgia will be recorded after 12 weeks of block

Time frame
After 12 weeks of block

Secondary outcomes

1

Blood pressure

Blood pressure will be recoded at time of block and following up at first 24 hours.

Time frame
24 hours postoperatively
2

Heart rate

Heart rate will be recoded at time of block and following up at first 24 hours.

Time frame
24 hours postoperatively
3

Oxygen saturation

Oxygen saturation will be recoded at time of block and following up at first 24 hours.

Time frame
24 hours postoperatively
4

Time to first rescue analgesia

Time to first rescue analgesia will be recorded from the end of surgery till first dose of Acetaminophen administrated.

Time frame
24 hours postoperatively

Other outcomes

Sponsors and contacts

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