Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorNamik Kemal University
About this trial
This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block (EOIPB) in patients undergoing elective open nephrectomy under general anesthesia. Sixty adult patients will be randomized to receive either ESPB or EOIPB before surgical incision. All participants will receive standardized general anesthesia and postoperative multimodal analgesia. Postoperative pain scores, opioid consumption, rescue analgesic requirements, and postoperative nausea and vomiting will be assessed during the first 24 hours after surgery. The study aims to determine whether one fascial plane block technique provides superior postoperative pain control and recovery following open nephrectomy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 18 and 65 years.
American Society of Anesthesiologists (ASA) physical status I or II.
Scheduled for elective open nephrectomy.
Able and willing to provide written informed consent.
Disqualifiers
Refusal to participate or inability to provide informed consent.
Emergency surgery.
Body mass index (BMI) greater than 35 kg/m².
Known allergy or hypersensitivity to local anesthetics.
Trial design
Design model
Parallel
Treatments tested in this trial
Erector Spinae Plane Block
Procedure/SurgeryUltrasound-guided erector spinae plane block performed after induction of general anesthesia using 30 mL of 0.25% bupivacaine before surgical incision.
Modified External Oblique Intercostal Plane Block
Procedure/SurgeryUltrasound-guided modified external oblique intercostal plane block performed after induction of general anesthesia using 30 mL of 0.25% bupivacaine before surgical incision.
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: ESPB GroupExperimental treatment 1 intervention
Group B: EOIPB GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Pain intensity at rest
Postoperative pain intensity will be assessed at rest using the 11-point Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.
Time frame
0, 2, 6, 12, and 24 hours after surgerySecondary outcomes
1
Pain intensity during movement
Postoperative pain intensity will be assessed during movement using the 11-point Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.
Time frame
0, 2, 6, 12, and 24 hours after surgery2
Total Opioid Consumption
Total postoperative tramadol consumption recorded from patient-controlled analgesia during the first 24 postoperative hours.
Time frame
24 hours after surgery3
Rescue Analgesic Requirement
Number of patients requiring rescue analgesia during the first 24 postoperative hours.
Time frame
24 hours after surgery4
Postoperative Nausea and Vomiting
Incidence of postoperative nausea and vomiting during the first 24 postoperative hours.
Time frame
24 hours after surgerySponsors and contacts
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Source ClinicalTrials.gov