Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars

ConditionsDental Caries Pulp Necrosis Primary Tooth Pulpectomy Pediatric Dentistry Endodontic Infection

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age4-7

SponsorCairo University

About this trial

This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric patients. The study will assess bacterial reduction using blood agar

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Children aged 4 to 7 years

Clinically and radiographically diagnosed with nonvital primary molars requiring pulpectomy

Cooperative children who can undergo dental treatment

Healthy-appearing children with no systemic, physical, or mental disorders

Disqualifiers

Medically compromised or uncooperative children

Advanced root resorption (more than two-thirds)

Teeth near exfoliation

Deep subgingival caries preventing proper restoration

Trial design

Design model

Parallel

Treatments tested in this trial

Sodium hypochlorite
Drug
sodium hypochlorite solution will be used as a root canal irrigant during pulpectomy in primary molars. A volume of 3 mL will be delivered into each canal using a syringe with a side-vented needle. Irrigation will be followed by microbial sampling for blood agar
Moringa Oleifera Leaf Extract
Biological/Vaccine
extract of Moringa oleifera leaves will be used as an intracanal irrigant during pulpectomy. A volume of 3 mL will be used per canal, and post-irrigation microbial samples will be analyzed using the same methods as the control group.

Treatment groups

38 Participants

are divided into 2 treatment groups

Group A: Sodium Hypochlorite GroupExperimental treatment 1 intervention

Group B: Moringa oleifera Leaf Extract GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Zone of inhibition against Coagulase-Negative Staphylococci

"Primary Outcome: The antimicrobial efficacy of both types of irrigants... based on the diameter of the zone of inhibition

Time frame

"Day 1 (Pre- and post-irrigation samples collected during the same visit)"

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: