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Motor Sparing Techniques, Genicular Nerve Radiofrequency Ablation Has Emerged As a Viable Alternative to Conservative Therapy and Total Knee Arthroplasty

ConditionKnee Osteoarthritis \(OA\)
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50-70
SponsorAssiut University

About this trial

There has recently been considerable interest in the role of radiofrequency ablation (RFA) of the genicular nerves for KOA. In the majority of previous studies, ablation was done via a radiofrequency technique using either fluoroscopy or ultrasound for only three genicular nerves, whereas the knee joint is also supplied by a few other nerves (11, 12). Interestingly, neurolytic agents can also be used to ablate the nerves, and are readily available, less costly, and need less logistic support

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age from 50-70 years.

Both sexes.

American Society of Anesthesiology (ASA) physical status I-III.

Patients with 3rd and 4th degree of KOA pain who undergo knee articular branch denervation via RF ablation.

Disqualifiers

Deformities in knee.

Charcot joint (stiff Joint)

Acute knee injury

Previous ipsilateral total knee arthroplasty or radiofrequency denervation.

Trial design

Design model

Factorial

Treatments tested in this trial

  • Radiofrequency

    Procedure/Surgery

    There has recently been considerable interest in the role of radiofrequency ablation (RFA) of the genicular nerves for KOA. In the majority of previous studies, ablation was done via a radiofrequency technique using either fluoroscopy or ultrasound for only three genicular nerves, whereas the knee joint is also supplied by a few other nerves . Interestingly, neurolytic agents can also be used to ablate the nerves, and are readily available, less costly, and need less logistic support

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: three genicular nerves raiofrequency ablationActive comparator 1 intervention
Group B: eight genicular nerves radiofrequency ablationActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

vas score

will be assessed at 0, 1, and 4 weeks. on the Visual Analogue Scale (VAS) (0 = no pain, 10 = unbearable pain).

Time frame
4 weeks

Secondary outcomes

1

Total WOMAC score.

will be assessed at 0, 1, and 4 weeks

Time frame
4 weeks
2

seven-point Likert scale

seven-point Likert scale (one = worst ever, two = much worse, three = worse, four = not improved but not worse, five = improved, six = much improved, and seven = best ever).

Time frame
4 weeks
3

analgesic request

Time frame
4 weeks
4

adverse effects

Time frame
4 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: