Neuromuscular Training in Professional Esports Players

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-35
SponsorYeditepe University

About this trial

Professional esports players engage in prolonged training sessions and experience high physical and mental stress due to intensive competition schedules. These demands can lead to increased fatigue, decreased performance, and health problems. This randomized controlled trial aims to investigate whether adding a structured neuromuscular exercise program to routine esports training reduces fatigue and stress biomarkers and improves performance-related outcomes in professional esports players.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age between 18-35 years

Currently competing as a contracted professional esports player

Participating in ≥35 hours/week of training with their team

Voluntary agreement to participate and sign informed consent

Disqualifiers

History or presence of medical conditions affecting safety or performance: metabolic, cardiovascular, renal, neurological, or respiratory disorders

Playing esports only at amateur or beginner level

Answering "Yes" to any item in the Physical Activity Readiness Questionnaire (PAR-Q)

Participating in <35 hours/week esports training during the study

Trial design

Design model

Parallel

Treatments tested in this trial

  • Neuromuscular Training

    Behavioral

    A progressive neuromuscular exercise program including dynamic warm-up, aerobic exercises, functional strengthening of lower and upper extremity muscles, core stabilization training, and reaction drills performed 3 times per week for 8 weeks. Duration and repetitions increase biweekly according to a structured progression protocol.

  • Physical Activity Counseling

    Behavioral

    Structured physical activity counseling based on ACSM 5A principles (Assess, Advise, Agree, Assist, Arrange) delivered weekly for 8 weeks to promote sustainable physical activity behaviors and reduce sedentary time during esports training routines.

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: Neuromuscular TrainingExperimental treatment 1 intervention
Group B: Physical Activity CounselingActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Serum cortisol level - Stress Biomarkers

Serum cortisol level will be analyzed under fasting conditions using standardized laboratory protocols.

Time frame
Baseline and 8 weeks
2

Testosterone level - Stress Biomarkers

Testosterone level will be analyzed under fasting conditions using standardized laboratory protocols.

Time frame
Baseline and 8 weeks
3

C-Reactive Protein Level (CRP) - Fatigue Biomarkers

Serum CRP levels will be analyzed under fasting conditions using standardized laboratory protocols.

Time frame
Baseline and 8 weeks
4

Creatine Kinase (CK) Level - Fatigue Biomarkers

Creatine kinase levels will be analyzed under fasting conditions using standardized laboratory protocols.

Time frame
Baseline and 8 weeks.

Secondary outcomes

1

Muscle Strength

Hand, forearm, shoulder, and back muscle strength will be assessed using a handheld myometer; mean of three trials recorded in kilograms.

Time frame
Baseline and 8 weeks
2

Sleep Quality

Assessment of subjective sleep quality, sleep duration, sleep disturbances, and overall sleep efficiency with Pittsburgh Sleep Quality Index. The Pittsburgh Sleep Quality Index (PSQI) consists of 19 items that generate seven component scores, each ranging from 0 to 3, yielding a global score between 0 and 21, with higher scores indicating poorer sleep quality; a total score greater than 5 reflects clinically significant sleep disturbance.

Time frame
Baseline and 8 weeks
3

Physical Activity Level

Self-reported physical activity levels converted to MET-minutes per week. (IPAQ-Short Form). The International Physical Activity Questionnaire-Short Form (IPAQ-SF) provides total physical activity expressed in Metabolic Equivalent of Task (MET)-minutes/week, and scores are categorized as follows: \<600 MET-minutes/week indicates low activity, 600-3000 MET-minutes/week indicates moderate activity, and \>3000 MET-minutes/week indicates high physical activity level.

Time frame
Baseline and 8 weeks
4

Reaction Time

Average visual reaction time over 5 trials recorded in milliseconds. Average response latency to an auditory stimulus over 5 trials.

Time frame
Baseline and 8 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Yeditepe University

Lead sponsor

Istanbul University - Cerrahpasa

Collaborator