Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure \>=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The investigators are establishing a biobank to collect samples (blood, urine, stool) from patients with pulmonary hypertension, patients at high risk for pulmonary hypertension, healthy controls, and patients undergoing right heart catheterization. Specimens will be stored for future investigations.
Diagnosis of pulmonary hypertension and followed at the Comprehensive Pulmonary Hypertension Center OR
Diagnosis of systemic sclerosis and followed at the Comprehensive Pulmonary Hypertension Center OR
Diagnosis of mixed connective tissue disease and followed at the Comprehensive Pulmonary Hypertension Center OR
Undergoing outpatient right heart catheterization
Age<18
Pregnant
Unable to understand English
Currently incarcerated
Subjects will be enrolled from 2 venues: 1) Comprehensive Pulmonary Hypertension Center clinic (pulmonary hypertension, systemic sclerosis without PH, mixed connective tissue disease without PH) and 2) Outpatient right heart catheterization lab. Healthy subjects (age\>18, not currently smoking, no chronic medical conditions) will also be enrolled.
Other
Prospective
No intervention. Biospecimen collection only
Other interventionBiospecimen collection
Collection of biospecimens
Biospecimen collection only
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