New Treatment of Common Wart

ConditionCommon Warts (Verruca Vulgaris)

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorSohag University

About this trial

this study aims to compare the efficacy and safety of platelet rich fibrin injection versus intralesional vitamin D injection in the treatmentof common warts. PRF, as an autologous biological material , may enhance tissue regeneration and immune response.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

- Age more than or equal to 18 years

Clinically and dermoscopically confirmed Common warts of both sex

patient not receiving previous treatment at least one month before recruitment in our study

Single or multiple lesions suitable for injection.

Disqualifiers

Chronic Systemic desise (DM , HTN , Autoimmune , immunosuppressive disorders eg , lupus , renal or hepatic failure ) or Hematologic Conditions (anemia : hemoglobin level below 10 g/dl , thrombocytopenia : platelet count below 150,000 /µL ) Infectious Diseases , Local bacterial or fungal infection at the lesions .

Trial design

Design model

Parallel

Treatments tested in this trial

PRF group
Biological/Vaccine
intralesional PRF injection in common warts
Vitamin D
Drug
intralesional vitamin D injection in common wart

Treatment groups

70 Participants

are divided into 2 treatment groups

Group A: group 1 PRF injectionActive comparator 1 intervention

Group B: group 2 vitamin D injectionActive comparator 1 intervention

Trial outcomes

Primary outcomes

treatment of common wart by PRF injection ( Mild response: < 50% reduction in lesion size , Moderate response: ≥ 50% reduction in lesion size , to measure the change in lesion size , is the patient satisfied or not )

treatment of common wart by intralesional injection of PRF

Time frame

1 session every 2 weeks for 3 months

changes in common warts after treatment by PRF (measuring complete clearance and recurrence of the lesions ,asking about patient satisfaction )

Time frame

6 months after the last session

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sohag University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: