Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMakati Medical Center
About this trial
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are:
Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers will compare the novel barrier topical product to petrolatum (a gold standard occlusive barrier repair agent) to see how they are comparable in treating skin barrier dysfunction.
Participants will:
Apply the novel barrier topical product or petrolatum twice a day for 28 days Visit the clinic once a week for checkups and tests Keep a diary of their application of the assigned product
Eligibility criteria
Qualifiers
Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators.
Mild to moderate chronic plaque psoriasis, defined as total body surface area (BSA) involved: ≤3% to 10%.
Contact dermatitis
Seasonal xerosis or clinically evident skin dryness
Disqualifiers
Failure to meet any of the above inclusion criteria
Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatment
Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within 2 weeks
Open wounds or evidence of secondary infection at test sites
Trial design
Treatments tested in this trial
- Novel barrier repair topical product
- Petrolatum
Treatment groups
26 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov