About this trial
Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.
This study evaluates whether optic nerve sheath diameter (ONSD), measured using a non-invasive bedside ocular ultrasound technique, can help predict the development of PDPH.
Participants undergoing cesarean section with spinal anesthesia will undergo ONSD measurements at predefined perioperative time points. Participants will be followed postoperatively for the occurrence of headache.
The findings may help improve early recognition and management of PDPH.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Women aged 18 to 45 years
Singleton pregnancy
Planned cesarean section (elective or emergency due to fetal indications)
Spinal anesthesia planned for the procedure
Disqualifiers
Known ophthalmologic diseases affecting the optic nerve or retina (e.g., glaucoma, optic atrophy)
Active eye infection or recent ocular surgery
Known intracranial pathology affecting cerebrospinal fluid dynamics (e.g., intracranial mass, hydrocephalus, idiopathic intracranial hypertension)
History of stroke or subarachnoid hemorrhage
Trial population
The study population will consist of pregnant women aged 18-45 years undergoing cesarean section under spinal anesthesia at Kocaeli University Hospital. Participants who meet the eligibility criteria and provide informed consent will be enrolled.
Trial design
Cohort
Prospective
Treatments tested in this trial
Optic Nerve Sheath Diameter Measurement
Other interventionParticipants will undergo non-invasive ocular ultrasound measurement of optic nerve sheath diameter at five predefined time points: preoperatively, 10 minutes after spinal anesthesia, at the end of surgery, at postoperative 24 hours, and at postoperative 48 hours.
Treatment groups
Trial outcomes
Primary outcomes
Association Between Optic Nerve Sheath Diameter Measurements and Post-Dural Puncture Headache
Assessment of the association between optic nerve sheath diameter measurements and the development of post-dural puncture headache.
Sponsors and contacts
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