Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorJohns Hopkins University
About this trial
This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Children (age<18)
Pregnant females
Developmentally delayed subjects
Subjects unable to provide informed consent
Trial design
Design model
Parallel
Treatments tested in this trial
Swept-Source (SS) OCT Angiography
DeviceNon-invasive, minimal risk, ocular imaging study
Spectral-Domain (SD) OCT Angiography
DeviceNon-invasive, minimal risk, ocular imaging study
Fundus Imaging
DeviceNon-invasive, minimal risk, ocular imaging study
Axial Length Measurement Device
DeviceNon-invasive, minimal risk, ocular imaging study
Treatment groups
1,050 Participants
are divided into 4 treatment groupsGroup A: ControlsOther 4 interventions
Group B: Diabetics with and without Diabetic Retinopathy OnlyOther 4 interventions
Group C: Hypertension OnlyOther 4 interventions
Group D: Diabetics w/ or w/o Diabetic Retinopathy & HypertensionOther 4 interventions
Trial outcomes
Primary outcomes
1
Correlation of Imaging
Correlation of diagnostic imaging findings (vessel skeleton density) from OCT based images with disease stage
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Johns Hopkins University
Lead sponsor
National Eye Institute (NEI)
Collaborator
Source ClinicalTrials.gov