About this trial
Ectodermal dysplasia is a rare inherited condition that affects structures derived from the ectoderm, including teeth, skin, hair, and sweat glands. Dental findings are often severe and include missing or malformed teeth and poorly developed jaw ridges. These abnormalities can significantly affect chewing, speech, facial appearance, and quality of life, especially in children and young adults. Removable dentures, particularly overdentures when some teeth are present, are commonly used to restore function and appearance in these patients because they are conservative and cost-effective. However, conventional acrylic dentures may show dimensional changes during processing, which can lead to poor denture fit, reduced retention, and lower patient satisfaction. Three-dimensional (3-D) printed dentures are a newer digital fabrication method that may reduce material shrinkage and improve denture adaptation. Despite these potential advantages, clinical evidence comparing 3-D printed and conventional overdentures in patients with ectodermal dysplasia remains limited, highlighting the need for well-designed clinical studies.
The purpose of this study is to compare patient satisfaction and denture base adaptation between 3-D printed maxillary overdentures and conventional acrylic maxillary overdentures in patients with ectodermal dysplasia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age must range from 10-35 years.
Must have a few remaining teeth in the maxilla.
Must will to attend all follow-ups.
Disqualifiers
Extreme anatomical limitations such as a large torus that requires surgical excision.
Allergy to dentures made of resins.
Pathological changes of residual ridges as recurrent or persistent ulcers, osteomyelitis and infections.
Trial design
Crossover
Treatments tested in this trial
3-D printed overdenture
DeviceOverdenture is constructed using 3 -D printing technology not conventional processing of acrylic resin
Conventional overdenture
Deviceoverdentures will be constructed using Conventional acrylic processing method
Treatment groups
Trial outcomes
Primary outcomes
Patient satisfaction
Patient satisfaction will be measured using patient satisfaction questionnaire in ordinal scale. It uses a 5- point Likert scale to give a removable denture satisfaction index.
Secondary outcomes
Denture adaptation
Denture adaptation will be measured using surface matching software in deviation values. Unit is µm.
Sponsors and contacts
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