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Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars

ConditionsPulp Disease, DentalPulp Therapy in Primary MolarsPulpitis - ReversiblePulp InflammationVital Pulp TherapiesCarious Exposure of PulpPrimary Molar ToothPrimary Molar Pulpotomy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age4-8
SponsorCairo University

About this trial

This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Uncooperative children.

Medically compromised children.

Patients whose parents refuse to participate or refuse to sign the informed consent.

Previously accessed molars.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Oxymetazoline 0.05% nasal solution

    Other intervention

    Using 1 drop (\~0.05 mL) of 0.05% OXY (Normifrin Nasal spray, MUP, Egypt, and generic equivalents) delivered through a micro- brush or a small cotton pellet over pulp stumps to achieve hemostasis.

  • Sodium Hypochlorite Solution

    Other intervention

    Compression of a sterile cotton pellet soaked in 5% NaOCl over the pulpal stumps for 5 min

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Using sodium hypochlorite as hemostatic agent in MTA pulpotomy of primary molarsActive comparator 1 intervention
Group B: Using Oxymetazoline as hemostatic agent in MTA pulpotomy of primary molars.Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Clinical Success.

•Spontaneous pain: will be evaluated by asking the patient and/or guardian. Unit of measurement: Binary.

Time frame
Clinical evaluation will be performed at 1,3 &6 months postoperatively
2

clinical success

Pain to percussion: will be tested through percussion test (using the back of the dental mirror). Unit of measurement: Binary

Time frame
Clinical evaluation will be performed at 1,3& 6 months postoperatively.
3

Clinical success:

• Sinus or fistula: will be evaluated through visual examination. Unit of measurement: Binary (yes or No)

Time frame
Clinical evaluation will be performed at 1,3&6 months postoperatively.
4

Clinical success

Pathologic mobility: will be evaluated by mobility test (pressure using the ends of two dental mirrors.) Unit of measurement: Binary (yes or No)

Time frame
Clinical evaluation will be performed at 1,3&6 months postoperatively.

Secondary outcomes

1

Radiographic success.

* Internal and external root resorption: will be evaluated by intraoral digital periapical X-ray. * Unit of measurement: Binary (yes or No).

Time frame
Radiographic evaluation will be performed at 3 & 6 months postoperatively.
2

Radiographic success

Furcal abscess: will be evaluated by intraoral digital periapical X-ray. • Binary outcome

Time frame
Radiographic evaluation will be performed at 3 & 6 months postoperatively.
3

Radiographic succces

Widening of PDL: will be evaluated by intraoral digital periapical X-ray. Binary outcome

Time frame
Radiographic evaluation will be performed at 3 and 6 months postoperatively.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: