Pain Phenotypes in Individuals With Multiple Sclerosis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKutahya Health Sciences University
About this trial
This observational cross-sectional study aims to determine chronic pain phenotypes in individuals with multiple sclerosis (MS) and to investigate the clinical characteristics associated with different pain phenotypes. Participants with MS and chronic pain will undergo a comprehensive clinical assessment to identify nociceptive, neuropathic, nociplastic, and mixed pain phenotypes. The assessment will include clinical history, pain characteristics and distribution, quantitative sensory testing, pain intensity, disease severity, fatigue, health-related quality of life, and pain catastrophizing. The clinical characteristics of participants with different pain phenotypes will subsequently be compared.
Eligibility criteria
Qualifiers
Age 18 years or older
Definite diagnosis of multiple sclerosis according to the McDonald criteria
No MS relapse or high-dose steroid treatment within the previous 3 months
Pain intensity ≥2 on the Numeric Rating Scale in at least one body region for at least 3 months
Disqualifiers
Pregnancy
Severe psychiatric disorder and/or severe cognitive impairment confirmed by a neurologist or neuropsychiatrist
Presence of a serious pathology or disease that may compromise the assessment process or affect clinical decision-making, including metastasis, cancer, untreated or unhealed fractures, neurological disorders other than multiple sclerosis, or a history of diabetes
Trial design
Treatments tested in this trial
- Pain classification method
Treatment groups
No treatment groups listed
Sponsors and collaborators
Source ClinicalTrials.gov