Periodontitis on Gingival Crevicular Fluid Metobolomics
ConditionPeriodontitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorUniversity of Catania
About this trial
This cross-sectional observational study will compare the gingival crevicular fluid metabolomic profile of 30 adults with periodontitis and 30 periodontally healthy adults. Participants will undergo a periodontal examination and gingival crevicular fluid collection during a single study visit. Targeted metabolomic analysis will be used to identify differences between the two groups and associations with periodontal clinical parameters.
Eligibility criteria
Qualifiers
Age between 18 and 70 years.
Ability to understand the study procedures and provide written informed consent.
For the periodontitis group: diagnosis of periodontitis according to the 2018 classification of periodontal diseases.
For the healthy control group: periodontal health according to the 2018 classification, with no current diagnosis or history of periodontitis.
Disqualifiers
Periodontal treatment during the previous 6 months.
Use of antibiotics, non-steroidal anti-inflammatory drugs, or immunosuppressive agents during the previous 6 months.
Pregnancy.
Trial design
Treatments tested in this trial
- Periodontal probing depth
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov