Perioperative Opioid-sparing Effect of Retrosuperior Costotransverse Ligament Block Versus Erector Spinae Block in Laparoscopic Cholecystectomy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-64
SponsorZagazig University

About this trial

This study aims to compare the analgesic effect of retro superior costotransverse ligament space block vs erector spinae plane block to Achieve high-quality perioperative opioid-sparing effect and postoperative analgesia after laparoscopic cholecystectomy with optimum hemodynamic stability and high patient and surgeon satisfaction

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

patient acceptance

Age: 21-64 years old.

Sex: both sexes.

Physical status: ASA I & II.

Disqualifiers

Known hypersensitivity to lidocaine or bupivacaine.

Patients with respiratory insufficiency.

Coagulation disorders or taking drugs affect surgical hemostasis.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Retrosuperior costotransverse ligament block group

    Procedure/Surgery

    The patient will receive retrosuperior costotransverse ligament block

  • Erector spinae block group

    Procedure/Surgery

    The patient will receive erector spinae block.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Retrosuperior costotransverse ligament block groupActive comparator 1 intervention
Group B: Erector spinae block groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

The time to first call to rescue analgesia

The time to first call to rescue analgesia( the interval between the block injection till the NRS more than or equal 4) (naluphine) will be recorded

Time frame
24 hours

Secondary outcomes

1

To assess block characteristics (block performance time)

To assess block characteristics (block performance time) in minutes

Time frame
1 hour
2

Total intraoperative fentanyl consumption

Total intraoperative fentanyl required other than the induction dose in micrograms

Time frame
duration of surgery (up to 2 hours)
3

Pain intensity by Numerical Rating Scale

Analgesic parameters (Pain intensity at rest and at movement) by using Numerical Rating Scale (NRS) which will explained to patient as follows:0=no pain and 10= worst pain

Time frame
30 minutes after arrival to post anesthesia care unit , 2hours, 4hours, 6hours, 8hours, 12hours, 18 hours and 24hours postoperative
4

total amount of rescue analgesia

total amount of rescue analgesia if NRS≥4. in the first 24 hours.

Time frame
24 hours

Other outcomes

Sponsors and contacts

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