This study analyzes patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University from 2017 to 2024, focusing on anesthesia's impact on post-op results. It gathers patient data from hospital and Mediston systems, with main focus on in-hospital complications and secondary focus on ICU stay, post-op hospitalization, mortality, and intubation time. The research aims to deepen understanding of anesthetic management's role in lung transplant outcomes and guide improvements in perioperative anesthesia protocols.
Age >18 years at time of transplantation
Received single or bilateral lung transplantation
Re-transplantation
Multi-organ transplantation
Autotransplantation
Incomplete medical records: Recipients with >20% missing essential data elements in any of these categories:Preoperative baseline characteristics； Intraoperative parameters；Postoperative outcome measures
Patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University between January 2017 and October 2024
Cohort
Retrospective
Not listed
In-hospital adverse events
In-hospital adverse events were defined as post-transplant complications occurring prior to discharge, such as: Grade 3 PGD, respiratory infections, stroke, cardiac events, AKI, or liver impairment.
ICU stay
The ICU stay （days） was calculated from the time of ICU admission after surgery completion to actual discharge from the intensive care unit
Postoperative hospital stay
Postoperative hospital（days）stay after lung transplantation
In-hospital mortality
The proportion of patients who died during the initial hospitalization period following lung transplantation surgery
30-day postoperative mortality
Number of deaths within 30 days post-transplant) / (Total number of lung transplant recipients) × 100%；
Grade 3 Primary Graft Dysfunction (PGD)
PGD3:A ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO₂/FiO₂) \< 200 mmHg with bilateral infiltrates on chest radiograph, or Requirement for extracorporeal life support (ECLS) within 72 hours postoperatively, or use of inhaled pulmonary vasodilators for \>48 hours during mechanical ventilation.
Pulmonary Infection
Radiologically confirmed by a staff radiologist as new or progressive pulmonary infiltrates on: Chest X-ray or Computed tomography (CT) scan
Acute Kidney Injury
A rise in serum creatinine \>120 μmol/L
Cardiovascular Events
Acute myocardial infarction； heart failure；Cardiovascular hemorrhage；Clinically significant arrhythmias；Conduction system disorders；Cardiac arrest；Refractory hypotension due to cardiogenic sock.
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