Personality Traits and Biochemical Risk Phenotypes
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMedical Center TOPMED
About this trial
This prospective observational study investigates the association between personality traits and routine laboratory abnormalities in adults undergoing routine health assessment. Personality traits are assessed using the Five-Factor Personality Inventory (FFPI), while biochemical data are obtained from routine laboratory testing, including markers of glycemic status, liver function, lipid metabolism, renal function, and complete blood count parameters.
The primary objective of the study is to evaluate the association between FFPI personality trait scores and the total number of laboratory abnormalities identified during routine clinical evaluation. Secondary analyses will examine associations between personality traits and glycemic status, fasting plasma glucose concentration, liver function markers, lipid profile parameters, renal function indicators, complete blood count parameters, and the total number of laboratory abnormalities.
The findings may contribute to a better understanding of the relationship between psychological characteristics and biological health indicators and may support the development of more personalized approaches to health promotion, risk assessment, and disease prevention.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adults aged 18 years or older
Undergoing routine health assessment
Completion of the Five-Factor Personality Inventory (FFPI)
Availability of routine laboratory test results
Disqualifiers
Age younger than 18 years
Incomplete FFPI assessment
Missing or incomplete laboratory data
Refusal or inability to provide informed consent
Trial population
Adults undergoing routine health assessment in a clinical setting who complete the Five-Factor Personality Inventory (FFPI) and have routine laboratory data available for evaluation of laboratory health indicators and their association with personality traits.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
1,000 Participants
are grouped into 1 trial groupGroup A: Routine Health Assessment Cohort
Trial outcomes
Primary outcomes
1
Number of Laboratory Abnormalities
Total number of routine laboratory parameters outside their corresponding reference intervals, expressed as a count of abnormal laboratory findings. Laboratory parameters include fasting plasma glucose (mg/dL), gamma-glutamyl transferase (GGT, U/L), alanine aminotransferase (ALT, U/L), aspartate aminotransferase (AST, U/L), total cholesterol (mg/dL), serum creatinine (mg/dL), urea (mg/dL), estimated glomerular filtration rate (eGFR, mL/min/1.73 m²), and complete blood count parameters measured according to standard laboratory units.
Time frame
At baselineSecondary outcomes
1
Five-Factor Personality Inventory (FFPI) Scores
Personality traits assessed using the Five-Factor Personality Inventory (FFPI), including Neuroticism, Extraversion, Agreeableness, Conscientiousness, and Openness dimensions, expressed as standardized questionnaire scores.
Time frame
At baseline2
Glycemic Status
Classification of participants according to fasting plasma glucose (mg/dL) concentration measured during routine laboratory assessment as: Normoglycemia (\<100 mg/dL) Prediabetes (100-125 mg/dL) Hyperglycemia (≥126 mg/dL or previously diagnosed diabetes mellitus)
Time frame
At baselineSponsors and contacts
Click on the lead sponsor to view all of their trials.
Medical Center TOPMED
Lead sponsor
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Collaborator
Source ClinicalTrials.gov