Health TrialsbyHealthPanel

Antibacterial Effect and Post-operative Pain Following Various Techniques of Intracanal Heating of NaOCL

ConditionNecrotic Teeth
Trial statusNot yet recruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorMisr University for Science and Technology

About this trial

The goal of this clinical trial is to is to assess the antibacterial effect of sodium hypochlorite heated inside root canals of necrotic teeth using various activation techniques

The main question it aims to answer is:

Does the antibacterial effect vary following various standardized techniques of intracanal heating of sodium hypochlorite in endodontic treatment?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

adult male or female patients

medically free.

asymptomatic necrotic single rooted teeth

teeth with mature root

Disqualifiers

Patients with dental related symptoms

patients with chronic or systemic diseases

pregnant females.

multirooted teeth

Trial design

Design model

Parallel

Treatments tested in this trial

  • System-B

    Device

    The irrigation activation by heating is achieved using System-B heat carrier

  • Ultrasonic activation

    Device

    Activation of irrigation using ultrasonic

Treatment groups

36 Participants
are divided into 3 treatment groups
Group A: Intracanal heating for activation using ultrasonicsActive comparator 1 intervention
Group B: Intracanal heating for activation using System-B heat carrierExperimental treatment 1 intervention
Group C: Intracanal heating for activation using a combination of ultrasonics and System-BExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Bacterial reduction

Antibacterial effect is evaluated by counting number of bacterial colonies, samples are collected and placed in brain-heart infusion (BHI) broth and subjected to microbiological analysis to determine the colony-forming unit (CFU)/ml

Time frame
after treatment, samples are sent to microbiology lab and bacterial count is measured day 1 after treatment.

Secondary outcomes

1

Post-operative pain

Postoperative pain is assessed for each patient using Visual Analog Scale (VAS) with a score ranging from 0 (no pain) to 10 (unbearable pain)

Time frame
Post operative pain is measured until day 3 after treatment

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Misr University for Science and Technology

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: