Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age16-50
SponsorMisr University for Science and Technology

About this trial

This clinical trial will be conducted to assess the clinical efficacy of using Antivet cleaning enamel solution or hydrochloric acid and phosphoric acid in microabrasion technique for mild to moderate intrinsic stained teeth.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with moderate to mild stained teeth.

16-50 years.

Males or Females.

Co-operative patients approving to participate in the study.

Disqualifiers

High caries index with poor oral hygiene.

Severe medical complications.

Pregnancy.

Xerostomia.

Trial design

Design model

Parallel

Treatments tested in this trial

  • (Antivet, MDC DENTAL, Zapopan Jalisco México)

    Drug

    specially formulated to eliminate stains on the enamel surface caused by dental fluorosis or any other external factor.The tooth's surface is exposed to an acid solution by ionization by the fluoride absorbed in the apatite crystals (stains). This reaction allows for the fluoride ions to separate from the fluoride ions in the apatite crystals, forming soluble salts that are easily removed from the tooth enamel surface. Once the stains are removed, a calcium hydroxide solution is applied to neutralize the residual acidic solution left on the tooth surface. Lastly, the tooth is rinsed with water.Acid Base (Antivet): It is hydrofluoric acid at a 21% concentration stabilized by an organic tricarboxylic acid, with a controlled pH of \<3, necessary to react with the fluoride ions to form soluble salts. The organic and inorganic ions are extracted from within the fluorapatite crystals through this ionization process which essentially allows the enamel surface to be cleansed without damaging it

  • Opalustre

    Drug

    technique involves employing a mixture 6.6% hydrochloric acid with silica carbide particles, with rubber cup in slow rotating motion to the areas of discoloration or white opacities for 60 seconds. The teeth will be rinsed with water between slurry applications. Depending on the stain reduction, microabrasion will be repeated up to six times during the same appointment to achieve the desired result. .

  • phosphoric acid 37% and aluminium oxid 50 microns

    Drug

    ● Equal quantities from phosphoric acid 37% and aluminium oxid 50 microns will be mixed, thick mix will be applied on the affected tooth/teeth and will be rubbed with a rubber cup in a low-speed contra-angle handpiece for 60 seconds of each application. Every patient will be received the entire microabrasion treatment in a single appointment with a maximum of 6 applications.

Treatment groups

60 Participants
are divided into 3 treatment groups
Group A: phosphoric acid 37% and aluminium oxid 50 micronsActive comparator 1 intervention
Group B: Opalustre™Active comparator 1 intervention
Group C: AntivetExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Clinical performance

visual analog scale using scoring system

Time frame
three months

Secondary outcomes

Other outcomes

Sponsors and contacts

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