Simple Non-cultured Endothelial Cell Therapy for Corneal Endothelial Dysfunction
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSingapore Eye Research Institute
About this trial
Assessment of safety and efficacy of cell injection therapy generated using non-cultured human corneal endothelial cells in treating corneal endothelial dysfunction
Eligibility criteria
Qualifiers
None
Disqualifiers
Severe forms or late-stage presentation of corneal decompensation with severe corneal stromal scarring and or scarring to the DM, unsuitable for SNEC-I.
Patients with complex anterior segment complications precluding a successful SNEC-I procedure
Patients who have other forms of endothelial dystrophy, traumatic corneal decompensation, or post-inflammatory corneal decompensation
Post-laser iridotomy or glaucoma related corneal decompensation
Trial design
Treatments tested in this trial
- Cell injection
Treatment groups
20 Participants
are divided into 1 treatment groupSponsors and collaborators
Singapore Eye Research Institute
Lead sponsor
L.V. Prasad Eye Institute
Collaborator
Source ClinicalTrials.gov