A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy

Trial statusNot yet recruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age10+
SponsorJazz Pharmaceuticals

About this trial

This study is being conducted to evaluate the safety and efficacy of JZP926 capsule in participants with Juvenile Myoclonic Epilepsy (JME).

Eligibility criteria

Qualifiers

Is ≥ 10 years of age at the time of screening.

Has a diagnosis of JME per ILAE criteria as specified in the protocol.

Has at least 4 myoclonic seizure days per 28 days historical seizure frequency.

Disqualifiers

Presence of seizure types other than GTC, myoclonic, and absence seizures.

If historical MRI has been performed, participant's MRI reveals a cause of epilepsy other than JME.

Has a concurrent, confirmed diagnosis of non-epileptic seizures or events that can confound the assessment of the efficacy measures, in the opinion of the investigator.

The etiology of the participant's seizures is a progressive neurologic disease.

Trial design

Treatments tested in this trial

  • JZP926 capsule
  • Placebo

Treatment groups

260 Participants
are divided into 3 treatment groups

Sponsors and collaborators