Juvenile Myoclonic Epilepsy

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Review clinical trials related to Juvenile Myoclonic Epilepsy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy

This study is being conducted to evaluate the safety and efficacy of JZP926 capsule in participants with Juvenile Myoclonic Epilepsy (JME).

Participants needed: 260
Trial details
Phase: Phase 2, Phase 3Age: 10+Biological sex: AllType: InterventionalSponsor: Jazz PharmaceuticalsUpdated: Jul 24, 2026Locations: 10
Eligibility criteria

Is ≥ 10 years of age at the time of screening. [+2]

Presence of seizure types other than GTC, myoclonic, and absence seizures. [+12]

Status: Recruiting

Biology of Juvenile Myoclonic Epilepsy

The investigators are collecting genetic information through blood samples as well as clinical and EEG data from over 1000 people with Juvenile Myoclonic Epilepsy (JME) across the UK, Europe and North America. This study will draw on both existing and new samples from JME patients. These will be compared to anonymised data from samples for 2000 controls. The goal of this study is to find the genetic cause of JME. Finding the cause will help create better treatments for JME, as well as improve patient outcomes by allowing us to detect it earlier.

Participants needed: 1,000
Trial details
Age: 10-40Biological sex: AllType: ObservationalSponsor: King's College LondonUpdated: Sep 5, 2025Locations: 15
Eligibility criteria

Diagnosis of Juvenile Myoclonic Epilepsy in accordance with Consensus criteria [+4]

Myoclonus only associated with carbamazepine or lamotrigine therapy [+5]