Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
ConditionPostoperative Pain
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18-65
SponsorBrigham and Women's Hospital
About this trial
This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive hysterectomy under general anesthesia.
Eligibility criteria
Qualifiers
Ages 18-65 years old
ASA category 1-3
Scheduled to undergo minimally invasive hysterectomy
No documented allergy to oxytocin
Disqualifiers
American Society of Anesthesiologists (ASA) group 4 or greater
Age >65 years old
Additional surgical procedures including but not limited to minor laparotomy, omentectomy, cystectomy, vaginectomy, and/or ablation of endometriosis.
Active opioid prescription of the equivalent of oxycodone >10 mg /day
Trial design
Treatments tested in this trial
- Oxytocin
- Placebo
Treatment groups
152 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov