About this trial
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are:
* Incidence of SSI after intervention * Length of hospital stay
Participants will be randomly assigned to two groups receiving either of the two groups:
Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation.
Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
• Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi
The age of patients should be between 18-60 years old.
Disqualifiers
Diabetic patients
Immune-suppressed patients
Patients taking steroids
Patients undergoing chemo-radiotherapy.
Trial design
Parallel
Treatments tested in this trial
0.9% saline solution
Procedure/SurgeryDuring emergency laparotomy, after the primary surgical procedure. the sheath will be sutured and the incision site will then be irrigated with three rounds of 1 liter of 0.9% saline solution, which will be completely aspirated before the closure of the incisional wound in experimental group.
Povidone-iodine Swab
Procedure/SurgeryNo intra-operative wound lavage done, and wound would be cleaned with povidone doused swab.
Treatment groups
Trial outcomes
Primary outcomes
Incidence of Superficial Surgical site infections
Development of Superficial Surgical Site Infection as determined by the CDC guidelines.
Secondary outcomes
Length of Hospital Stay
Number of in-hospital days (from time of admission to time of discharge)
Sponsors and contacts
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