Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-100
SponsorNovartis Pharmaceuticals

About this trial

This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD).

Eligibility criteria

Qualifiers

Able and willing to sign the informed consent (IC)

Patients with a diagnosis of AD and onset of disease for at least 1 year

Moderate to severe AD

Disqualifiers

Participants with a clinically significant medical condition or infectious disease (specified in sub-protocol)

Participants with clinically significant abnormal hematology, clinical chemistry, or urine test results or clinically significant abnormal ECG

Participant with any other active inflammatory skin disease

Participants with any chronic, uncontrolled medical condition, which would put the participant at increased risk during the study (e.g., uncontrolled: diabetes, hypertension)

Trial design

Treatments tested in this trial

  • GHZ339
  • Placebo

Treatment groups

224 Participants
are divided into 5 treatment groups

Sponsors and collaborators