Treatment of Periodontitis by Tulsi Gel

ConditionsAdvanced Periodontitis Stage III Periodontitis Stage IV Periodontitis

Trial statusNot yet recruiting

Trial phasePhase 2, Phase 3

Trial typeInterventional

Biological sexAll

Age30-50

SponsorAl-Azhar University

About this trial

This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis. Clinical parameters measurements, microbiological and radiographic assessment will be performed at base line, one month and 3 months after the intervention.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All patients included in this study will be having advancedI Periodontitis

Aging from 30 to 50 years old

Free from any local or systemic risk factors that may affect the results of the study.

Disqualifiers

Long-term therapy with medications within a month prior to enrollment that could affect periodontal status or healing.

Pregnant woman and lactating mothers.

Patients with previous periodontal treatment including scaling and root planning and periodontal surgery in the last 3 and 6 months, respectively.

Trial design

Design model

Parallel

Treatments tested in this trial

Tulsi gel
Drug
After scaling and root debridement, 4% of Tulsi gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
Chlorhexidine gel
Drug
After scaling and root debridement, 1% of Chlorhexidine gel will be injected in to the sulcus until it over flooded, at base line, then after one month.

Treatment groups

24 Participants

are divided into 2 treatment groups

Group A: Tulsi Gel groupActive comparator 1 intervention

Group B: Chlorhexidine Gel groupActive comparator 1 intervention

Trial outcomes