About this trial
The purpose of this study is to evaluate the drug levels, efficacy, and safety of Deucravacitinib (BMS-986165) in pediatric participants with juvenile psoriatic arthritis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Participants must have been diagnosed with Juvenile Psoriatic Arthritis (JPsA).
Participants must have at least three joints that are affected by arthritis.
Participants must have tried at least one type of medicine for JPsA for at least three months, but it didn't work well or caused problems.
Disqualifiers
Participants must not have been diagnosed with JPsA before 5 years of age.
Participants must not have other types of Juvenile Idiopathic Arthritis (JIA) that aren't JPsA,
Participants must not have a history of chronic eye inflammation (uveitis), or were diagnosed with uveitis within the last three months.
Other protocol-defined Inclusion/Exclusion criteria apply.
Trial design
Parallel
Treatments tested in this trial
Deucravacitinib
DrugSpecified dose on specified days
Placebo
Other interventionSpecified dose on specified days
Treatment groups
Trial outcomes
Primary outcomes
Time to first flare during the withdrawal period
Secondary outcomes
Trough concentration at steady state (Cminss)
Time-averaged steady-state concentration (Cavgss)
Steady-state maximum observed concentration (Cmaxss)
Number of participants with flare during the withdrawal period
Sponsors and contacts
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