About this trial
This study aims to investigate the impact of antibiotic prophylaxis on reducing wound infection rates following open repair of primary elective groin hernias in high-risk patients.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Volunteer to participate in the study.
Elderly patients aged over 60 years.
Patients with Diabetes.
Or obese patients with a BMI greater than 35.
Disqualifiers
Non-cooperative patients for regular follow-up.
Therapeutic Indication for.
Trial design
Parallel
Treatments tested in this trial
Cefazolin 1000 MG
Drug* Medication: Cefazolin * Dosage: 1 gram * Administration Timing: A single dose will be administered preoperatively.
Treatment groups
Trial outcomes
Primary outcomes
Overall Complication Rate
Overall complication rate; graded by the Clavien- Dindo complications classification system
Wound infection/ Surgical site infection
has been defined and classified as superficial incisional, deep incisional, and organ/ space\_ surgical site infection by the Centers for Disease Control and Prevention (CDC) (Anderson 2014; Ban 2017; Berríos-Torres 2017).
Secondary outcomes
Mortality Rate
The measure of the number of deaths at the end of the study.
Hospital stay
In days: Number of days, patient in hospital since admission.
Other outcomes
Other Adverse events
Any adverse events will be observed during the follow-up period.
Sponsors and contacts
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University of Aleppo
Lead sponsor
Aleppo University Hospital Resident Team
Collaborator