Using of Bone Marrow Stem Cell Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Reconstruction of Upper Jaw Bony Cystic Defects, Comparing with Platelet Rich Fibrin with Bone Graft

ConditionMaxillary Cyst

Trial statusNot yet recruiting

Trial phasePhase 3

Trial typeInterventional

Biological sexAll

Age18-50

SponsorCairo University

About this trial

Will the use of bone marrow stem cells with platelet rich fibrin enhance and accelerate the bone regeneration in the upper jaw cystic defects ?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age range 18-50 years

Patients with a critical size maxillary cyst. (>3 cm)

Patients that free of any significant medical conditions that could affect healing or outcomes.

Disqualifiers

Patients with large jaw cyst that endanger vital structures

Patients with significant medical condition

age under 18 years

Trial design

Design model

Parallel

Treatments tested in this trial

Bone marrow stem cells concentrate , platelet rich fibrin , bone graft
Biological/Vaccine
All participants will be treated with Bone marrow stem cells concentrate , platelet rich fibrin , bone graft.
platelet rich fibrin and bone graft
Biological/Vaccine
All participants will treated with platelet rich fibrin PRF , bone graft.

Treatment groups

22 Participants

are divided into 2 treatment groups

Group A: Group A (Stem cells ,PRF group) intervention groupExperimental treatment 1 intervention

Group B: Group B (PRF group)Active comparator 1 intervention

Trial outcomes

Primary outcomes

cyst volume

volumetric analysis of cystic defect 3, 6 months after treatment .

Time frame

preoperative and 3, 6 months postoperative.

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: