The goal of this clinical trial is to learn whether a supervised physical activity program can be successfully carried out for adults living with obesity and depression, and whether people are willing to take part in this kind of research. The main questions it aims to answer are:
Can researchers recruit enough participants and keep them in the study? Will participants attend the physical activity sessions? Does physical activity change how depression symptoms are connected to each other over time?
Researchers expect that the study procedures and the physical activity program will be feasible and acceptable, based on goals set before the study began. Researchers also expect that physical activity will weaken the connections between depression symptoms over time and will lower depression symptoms overall. This second idea will be tested more fully in a future, larger trial.
Researchers will compare a supervised physical activity program to usual care to see whether the program can be delivered as planned and is acceptable to participants.
Participants will:
* Take part in a physical activity program led by a kinesiologist, twice a week for 9 weeks, or receive usual care plus information about physical activity and mental health support * Have a health check-up before and after the program * Answer short questions about their mood several times a day using a phone app * Take part in an interview after the program ends
Adult (≥ 18 years old)
Body mass index (BMI) ≥ 30 kg/m²
Mild to moderate depressive symptoms (Montgomery-Åsberg Depression -Rating Scale [MADRS] score ≥ 7 and < 35)
Less than 90 minutes of moderate physical activity per week
Pregnant or breastfeeding
Absolute contraindication to physical activity (as determined by the Get Active Questionnaire)
Severe psychiatric comorbidity likely to interfere with participation or interpretation of results (bipolar affective disorder, schizoaffective disorder, schizophrenia, or severe post-traumatic stress disorder)
Unstable treatment or symptoms: any change to background treatment (pharmacological and/or psychotherapeutic) within the past 3 months, OR unstable symptoms over the past 3 months if not on medication
Parallel
Supervised Physical Activity Program
Other interventionParticipants will take part in an individually supervised physical activity program led by a trained kinesiologist, consisting of two 45-minute sessions per week for 9 weeks. The program will include aerobic activities (e.g., kickboxing, walking, running) and resistance exercises, selected based on each participant's preferences to support adherence. Participants will choose their preferred location (research center, community room, or outdoor park). Exercise intensity will be self-selected by participants during the first two weeks, then gradually progressed toward a moderate intensity target (50-60% of heart rate reserve), monitored using a heart rate monitor at each session.
Recruitment rate
Number of patients contacted per month for eligibility screening. Success threshold: ≥ 6 patients/month
Enrollment rate
Number of participants enrolled in the study per month
Study refusal rate
Percentage of eligible people who decline to participate
Eligibility rate
Percentage of screened individuals who meet eligibility criteria
Depressive symptom dynamics (EMA-MADRS)
Ecological Momentary Assessment version of the Montgomery-Åsberg Depression Rating Scale (EMA-MADRS), administered via the BEIWE smartphone application
Depressive symptoms (Self report/CES-D)
Center for Epidemiologic Studies Depression Scale (CES-D)
Depressive symptoms (clinician-rated/MADRS)
Montgomery-Åsberg Depression Rating Scale (MADRS)
Anxiety symptoms (GAD-7)
Generalized Anxiety Disorder 7-item Scale (GAD-7)
Click on the lead sponsor to view all of their trials.
Universite du Quebec en Outaouais
Lead sponsor
Institut du Savoir Montfort
Collaborator
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Collaborator
Université de Montréal
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
