Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHaseki Training and Research Hospital
About this trial
The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels. Pneumoperitoneum is the use of carbon dioxide gas to create space inside the abdomen during laparoscopic surgery.
The main question this study aims to answer is whether a longer pneumoperitoneum time is associated with changes in blood bicarbonate levels after surgery.
Participants are adults undergoing laparoscopic inguinal hernia repair as part of their routine medical care. Researchers will measure blood gas values, including bicarbonate levels, before surgery and again two hours after surgery. The change in bicarbonate levels will be compared with the duration of pneumoperitoneum during the operation.
The results of this study may help improve the understanding of metabolic changes that occur during laparoscopic surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥18 years
Patients undergoing laparoscopic inguinal hernia repair using the TAPP technique
Ability to provide informed consent
Disqualifiers
Pregnancy
Severe cardiovascular disease
Renal insufficiency
Patients requiring additional intra-abdominal surgical procedures
Trial population
Adult patients undergoing laparoscopic inguinal hernia repair (TAPP) at Haseki Training and Research Hospital will be included. Perioperative pneumoperitoneum duration and serum bicarbonate changes will be analyzed using blood gas measurements obtained preoperatively and at the second postoperative hour.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Laparoscopic Inguinal Hernia Repair (TAPP)
Procedure/SurgeryStandard laparoscopic inguinal hernia repair performed using the transabdominal preperitoneal (TAPP) technique as part of routine clinical care. Pneumoperitoneum duration during the procedure will be recorded for analysis.
Treatment groups
100 Participants
are divided into 1 treatment groupGroup A: Laparoscopic Inguinal Hernia Patients1 intervention
Trial outcomes
Primary outcomes
1
Change in Serum Bicarbonate Level
Difference between preoperative and postoperative second-hour serum bicarbonate levels measured by blood gas analysis in patients undergoing laparoscopic inguinal hernia repair. Unit of Measure: mmol/L
Time frame
Preoperative to postoperative 2 hoursSecondary outcomes
1
Postoperative Pain Score
Postoperative pain intensity measured using the Visual Analog Scale (VAS). The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores represent greater pain severity. Unit of Measure: VAS score (0-10)
Time frame
Within 24 hours after surgery2
Change in Arterial Blood pH
Change in arterial blood pH measured during pneumoperitoneum. Unit of Measure: pH
Time frame
Preoperative to postoperative 2 hours3
Early Postoperative Complications
Early postoperative complications occurring within the first 24 hours after laparoscopic inguinal hernia repair.
Time frame
Within 24 hours4
Change in Arterial Partial Pressure of Carbon Dioxide
Change in arterial PaCO₂ levels measured intraoperatively. Unit of Measure: mmHg
Time frame
Preoperative to postoperative 2 hoursSponsors and contacts
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Source ClinicalTrials.gov