Health TrialsbyHealthPanel

Post-Extraction Wound Healing in Elderly

ConditionWound Healing
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65-80
SponsorUniversity of Nebraska

About this trial

Patients presenting to the University of Nebraska Medical Center College of Dentistry for a posterior extraction will be offered participation in the study. Prior to extraction, subjects will undergo clinical measurements, xray, gingival crevicular fluid (GCF) and saliva sampling and a blood draw. Following atraumatic tooth extraction, the subjects will be reevaluated for healing at 1, 2-weeks and 3 months. At each appointment, GCF, saliva and wound fluid (WF) will be collected and at 3 months a second xray will be taken.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

needs posterior tooth extracted

no systemic conditions or meds affecting wound healing

non-smoker

Disqualifiers

systemic conditions or meds known to affect wound healing

smokers

Trial population

Study population will be made of patients at the UNMC College of Dentistry requiring posterior extraction, aged 65-80.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • tooth extraction

    Procedure/Surgery

    posterior tooth extraction

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Amount of Interleukin-1 beta (IL1-B) in gingival crevicular at baseline

Measurement of IL1B in GCF

Time frame
Baseline

Secondary outcomes

1

Bone Density

Change in bone density post-extraction

Time frame
3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Nebraska

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: