Post Operative Shivering Following Anesthesia

ConditionShivering, Spinal Anesthesia

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-45

SponsorSohag University

About this trial

The aim of this study is to compare the efficacy of magnesium sulphate, ondansetron, and dexmedetomidine in managing post-spinal anesthesia shivering. The primary aim is the time to cessation of shivering after drug administration, while secondary aim include hemodynamic parameters (heart rate, blood pressure, SpO₂ ) and the recurrence of shivering

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age from 18 to 45 years.

Both sexes.

American Society of Anesthesiologists physical status I, II

Scheduled for elective lower abdominal or lower limb surgeries under spinal anesthesia

Disqualifiers

Patients with known allergy to study drugs.

Patients with baseline body temperature outside the normal range (36-37.5°C).

History of thermoregulatory disorders, thyroid dysfunction, or neurological diseases.

Patients receive sedatives, antipsychotics, or antidepressants.

Trial design

Design model

Parallel

Treatments tested in this trial

Dexmedetomidin
Drug
•Group D (Dexmedetomidine Group): 0.5 µg/kg dexmedetomidine diluted in 100 mL of normal saline.
Mg (magnesium sulfate)
Drug
50 mg/kg magnesium sulphate diluted in 100 mL of normal saline.
Ondansetron 8 mg
Drug
8 mg ondansetron diluted in 100 mL of normal saline.

Treatment groups

60 Participants

are divided into 3 treatment groups

Group A: Mg sulphate groupExperimental treatment 1 intervention

Group B: dexmedetomidine groupExperimental treatment 1 intervention

Group C: ondansetron groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Time to cessation of shivering after drug administration.

Grade 0: No shivering. * Grade 1: Piloerection or peripheral vasoconstriction but no visible shivering. 4 * Grade 2: Muscular activity in only one muscle group. * Grade 3: Muscular activity in more than one muscle group. * Grade 4: Whole-body shivering.

Time frame

6 hours

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sohag University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: