Predicting Spinal Hypotension in Cesarean Section
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorTC Erciyes University
About this trial
This prospective observational study investigates the predictive value of anthropometric and hemodynamic indices for spinal anesthesia-induced hypotension (SAIH) during cesarean section. While spinal anesthesia is preferred for its rapid onset, SAIH remains a frequent complication risking maternal and fetal safety. The study enrolled parturients at Erciyes University, excluding those with hypertension or extreme weight/height. Preoperative measurements included BMI, waist circumference (WC), body roundness index (BRI), and modified shock index (MSI). Following standardized spinal anesthesia with hyperbaric bupivacaine (Harten's dosage), hemodynamic parameters and sensory block levels were monitored. This research aims to determine whether BRI and WC offer superior predictive utility compared with conventional markers such as BMI and MSI to enhance individualized risk assessment in obstetric anesthesia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
American Society of Anesthesiologists (ASA) Class II
Having regular antenatal visits
Singleton pregnancy at ≥37 weeks of gestation
Pregnant women aged 18-45 -
Disqualifiers
Those with eclampsia, those with preeclampsia
Undergoing an emergency cesarean section
Those with bleeding diathesis and those receiving anticoagulant therapy
With a history of carotid artery stenosis,
Trial population
Parturients undergoing cesarean section
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
321 Participants
are grouped into 1 trial groupGroup A: Spinal Anestezi CS
Trial outcomes
Primary outcomes
1
Incidence of Spinal Anesthesia-Induced Hypotension (SAIH)
The presence or absence of hypotension (binary variable) will be recorded. The predictive power of the independent variables (BMI, BRI, WC, MSI) for this condition will be evaluated using logistic regression. Nagelkerke's $R\^2$ was treated as a component of the analysis procedure, not as a measurement unit.
Time frame
From the time of spinal bupivacaine administration up to 30 minutes post-administration.Sponsors and contacts
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Source ClinicalTrials.gov