About this trial
Postoperative pain remains a significant clinical problem affecting recovery, mobilization, and patient satisfaction after surgery. Considerable interindividual variability exists in postoperative pain intensity even among patients undergoing the same surgical procedure. This variability may be influenced not only by the extent of surgical trauma but also by individual pain sensitivity and psychological factors such as preoperative anxiety.
The aim of this prospective observational study is to evaluate whether pain intensity reported during routine venous cannulation and preoperative anxiety levels assessed by the Amsterdam Preoperative Anxiety and Information Scale (APAIS) can predict early postoperative pain severity in patients undergoing elective laparoscopic cholecystectomy under general anesthesia. Venous cannulation pain will be assessed using a 0-10 visual analog scale (VAS), and anxiety levels will be measured preoperatively using APAIS. Postoperative pain will be evaluated at predefined time points within the first 12 hours after surgery using VAS scores and analgesic consumption. Identifying simple and easily obtainable preoperative predictors may allow individualized postoperative analgesic strategies for patients at higher risk of severe postoperative pain.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥18 years
ASA physical status I-III
Scheduled for elective laparoscopic cholecystectomy under general anesthesia
Ability to understand and use the Visual Analog Scale (VAS)
Disqualifiers
Emergency surgery
Conversion from laparoscopic to open surgery
Cognitive impairment or inability to communicate effectively
Chronic pain lasting longer than 3 months
Trial population
The study population includes adult patients undergoing elective laparoscopic cholecystectomy under standardized general anesthesia
Trial design
Cohort
Prospective
Treatments tested in this trial
APAIS Assessment
Other interventionPreoperative anxiety is evaluated using the Amsterdam Preoperative Anxiety and Information Scale (APAIS).Pain during routine venous cannulation is assessed using a 0-10 visual analog scale (VAS).
Treatment groups
Trial outcomes
Primary outcomes
Early Postoperative Pain Intensity
Postoperative pain intensity assessed using a 0-10 visual analog scale (VAS).
Secondary outcomes
Total Analgesic Consumption
Total amount of analgesic medications administered during the first 12 postoperative hours, including rescue analgesics.
Locations
Sponsors and contacts
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