The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries. The main question it aims to answer is:
• Does the use of intravenous prophylactic antibiotics or antimicrobial-coated sutures significantly reduce the occurrence of surgical site infection in children undergoing open groin surgeries?
Researchers will compare no antibiotic use to the use of intravenous prophylactic antibiotics, or antimicrobial-coated sutures to see if the use of intravenous prophylactic antibiotics and antimicrobial-coated sutures significantly reduces the occurrence of surgical site infection following open groin surgeries in children.
Participants will:
* Undergo open groin surgery with either the use of intravenous prophylactic antibiotic or antimicrobial-coated sutures or without antibiotic use * Visit the clinic on postoperative days 5, 13 and 30 for review of the surgical wounds for any sign of infection.
All patients with clinical conditions requiring daycase open groin surgery
Re-operations
Immunocompromised patients
Malnourished patients
Complicated groin pathologies e,g obstructed inguinal hernia
Parallel
Antimicrobial-coated sutures
DeviceUse of Antimicrobial-coated sutures to close all layers of the surgical wound following open paediatric groin surgery
Intravenous Cefuroxime
DrugIntravenous cefuroxime is given at the induction of anaesthesia
Placebo intravenous injection
Other intervention0.2ml of Vitamin Bco injection + 9.8ml sterile water
Surgical site infection
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Olawumi Olajide
Lead sponsor
Obafemi Awolowo University Teaching Hospital
Sponsor institution
