About this trial
This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of Egyptian schoolchildren.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Healthy Egyptian schoolchildren aged 6-12 years.
Good general health.
Mild to moderate dental plaque accumulation.
Parental/caregiver willingness to provide consent
Disqualifiers
Antibiotic or antimicrobial use within the last month.
Allergies to the mouthwash components.
Systemic diseases affecting oral health.
Orthodontic appliances or extensive dental restorations.
Trial design
Parallel
Treatments tested in this trial
Probiotic mouthwash
Other interventionPatients will be receive probiotic mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.
Ethyl lauroyl arginate mouthwash
Other interventionPatients will be treated with ethyl lauroyl arginate mouthwash and instructed to rinse 5ml twice daily for 30 seconds for 28 days.
Professional prophylaxis (scaling + polishing)
Other interventionPatients will receive professional prophylaxis (scaling + polishing) at baseline and will use only regular toothpaste twice daily, with no adjunctive mouthwashes over 28 days.
Treatment groups
Trial outcomes
Primary outcomes
S. mutans count
S. mutans count will be measured at baseline (0 day) and post-intervention (28 days).
Secondary outcomes
Plaque index score
The plaque index score is classified as: * Score 0; No plaque * Score 1; Mild plaque accumulated along the gingival margin * Score 2; Moderate plaques accumulated along the gingival margin * Score 3; Heavy plaques accumulated along the gingival margin and adjacent tooth surface. Plaque index score will be measured at baseline (0 day) and post-intervention (28 days).
Salivary pH
Salivary pH measurements will be carried out by pH strips or pH meter.
Sponsors and contacts
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