The goal of this clinical trial is to learn about the safety and outcome of prophylactic pacemaker implantation in patients with right bundle-branch block undergoing trans-catheter aortic valve (TAVI) implantation in patients with severe aortic stenosis and left ventricular ejection fraction.Participants will be randomized to:
* Prophylactic pacemaker implantation prior TAVI * Conservative strategy
Patients undergoing TAVI indicated by severe valvular aortic stenosis
Written informed consent
Left ventricular ejection fraction ≥ 40 %
Persistent RBBB in 12-lead electrocardiogram (RSR' pattern in V1-3, QRS duration > 120 milliseconds, and wide S wave in leads I, aVL, V5-6)
Other indications for pacemaker implantation or previously implanted pacemaker
Life expectancy < 1 year
No written informed consent
Parallel
Prophylactic pacemaker implantation
DevicePacemaker implantation prior the TAVI-procedure
Events in the control arm
Composite of all-cause mortality, unplanned pacemaker implantation and new onset of heart failure
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This trial is not recruiting at the moment. You can still explore other options:
