Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling
ConditionHealthy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorDrexel University
About this trial
In a neuroimaging session, study participants will repeatedly and intermittently report the content of their ongoing, self-generated experiences based on an experience-sampling protocol in which self-report ratings will be triggered based on real-time analysis of the participant's current brain state. The protocol will be conducted while participants are undergoing MRI scanning.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age between 18-35
Disqualifiers
History of psychiatric or neurological disorder
contraindication for MRI
Trial design
Design model
Single group
Treatments tested in this trial
Experience sampling
BehavioralParticipants will repeatedly and intermittently report the content of their ongoing, self-generated experiences based on an experience-sampling protocol in which self-report ratings will be triggered based on real-time analysis of the participant's current brain state. The protocol will be conducted while participants are undergoing MRI scanning.
Treatment groups
60 Participants
are divided into 1 treatment groupGroup A: Real-time fMRIExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Number of participants showing an association between self-reported arousal (simple rating scale) and fMRI activation level in anterior insula
Participants will rate their subject arousal level on trials that are triggered by anterior insula activation (using real-time fMRI analysis) and control trials not involving anterior insula activation. The outcome is the number of participants showing an association between self-reported arousal and fMRI activation in anterior insula.
Time frame
Two sessions over one monthSponsors and contacts
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Drexel University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov